Journal: NeuroSci

Article Title: Effect of High-Salt Diet on Memory and Behavior in Mice Expressing Human Apolipoprotein Epsilon-4 (APOE4) Allele

doi: 10.3390/neurosci7020043

Figure Lengend Snippet: Memory and learning: the male and female APOE3 and APOE4 mice were trained, and their memory and learning abilities were determined by the Barnes maze test. The bars represent latency to target hole (sec) data as the mean ± SE on normal-salt (0.4%), low-salt (0.1% NaCl) ( A ) and high-salt (4% NaCl) ( B ) diets, n = 7 in the low-salt treatment groups and n = 9 in the high-salt treatment groups. No sex differences were observed. Significance was calculated by Two-way ANOVA, followed by Bonferroni multiple comparison tests (* p < 0.05).

Article Snippet: The Barnes maze behavioral circular apparatus (San Diego Instruments (SDI), San Diego, CA, USA) was constructed of white ABS plastic and contained 20 circular holes (2-inch diameter), evenly spaced along the perimeter of the maze.

Techniques: Comparison

Journal: NeuroSci

Article Title: Effect of High-Salt Diet on Memory and Behavior in Mice Expressing Human Apolipoprotein Epsilon-4 (APOE4) Allele

doi: 10.3390/neurosci7020043

Figure Lengend Snippet: Memory in APOE3 and APOE4: 72 h after the 4th training day, memory to reach the target hole was measured by the Barnes maze test. Primary latency ( A , B ), primary errors ( C , D ), total nose pokes ( E , F ), and distance traveled ( G , H ) were measured. Each bar represents data as the mean ± SE, and n = 7 in the low-salt treatment groups and n = 9 in the high-salt treatment groups. No sex differences were observed. Significance was calculated by Two-way ANOVA, followed by Bonferroni multiple comparison tests. (* p < 0.05).

Article Snippet: The Barnes maze behavioral circular apparatus (San Diego Instruments (SDI), San Diego, CA, USA) was constructed of white ABS plastic and contained 20 circular holes (2-inch diameter), evenly spaced along the perimeter of the maze.

Techniques: Comparison